Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 16/20 | 0.42 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4128364 | 0.82 | ALOX5 (0.42) | PIM1PIM2ALOX5KDM4E | |
| Acetic Acid SCHEMBL4128367 | 0.82 | ALOX5 (0.42) | PIM1PIM2ALOX5KDM4E | |
| SCHEMBL6264140 | 0.70 | ALOX5 (0.65) | ALOX5 | |
| SCHEMBL4138655 | 0.69 | ALOX5 (0.46) | ALOX5 | |
| Acetic Acid SCHEMBL4635017 | 0.69 | ALOX5 (0.55) | ALOX5 | |
| Acetic Acid SCHEMBL4137023 | 0.69 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL5543407 | 0.69 | MAPT (0.50) | KDM4E | |
| SCHEMBL4356532 | 0.68 | ALOX5 (0.46) | PIM1PIM2ALOX5 | |
| SCHEMBL4356536 | 0.68 | ALOX5 (0.46) | PIM1PIM2ALOX5 | |
| Acetic Acid SCHEMBL4120750 | 0.68 | ALOX5 (0.40) | PIM1PIM2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | claimed |