Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.65 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.55 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262617 | 0.85 | ALOX5 (0.59) | ALOX5RAB9A | |
| SCHEMBL6262619 | 0.85 | ALOX5 (0.59) | ALOX5RAB9A | |
| SCHEMBL6262585 | 0.84 | KMT2A (0.57) | ALOX5DYRK1AMEN1KMT2A | |
| SCHEMBL6262587 | 0.84 | KMT2A (0.57) | ALOX5DYRK1AMEN1KMT2A | |
| SCHEMBL6266100 | 0.83 | DCTPP1 (0.54) | ALOX5MEN1RAB9AKMT2A | |
| Acetic Acid SCHEMBL4137023 | 0.82 | ALOX5 (0.55) | ALOX5 | |
| Acetic Acid SCHEMBL4635017 | 0.82 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL6263665 | 0.82 | ALOX5 (0.58) | ALOX5MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6268290 | 0.81 | DYRK3 (0.60) | ALOX5DYRK3CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6262556 | 0.81 | DYRK3 (0.60) | ALOX5DYRK3CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082363-A1 | THIAZOLONE COMPOUNDS FOR TREATMENT OF CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-09-09 | — | — | WO | claimed |
| WO-2005082363-A1 | THIAZOLONE COMPOUNDS FOR TREATMENT OF CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-09-09 | — | — | WO | disclosed |