Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 9/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668579 | 0.92 | F2 (0.35) | PDE4BF2TP53MAPTLMNA | |
| SCHEMBL4668570 | 0.89 | GFER (0.42) | FABP4DHODHADORA1MPOPDE4B | |
| Hydrochloric Acid SCHEMBL4669539 | 0.89 | GFER (0.41) | FABP4DHODHADORA1MPOPDE4B | |
| SCHEMBL14600212 | 0.87 | KDM4C (0.38) | FABP3FABP4DHODHADORA1F2 | |
| SCHEMBL14600248 | 0.85 | DHODH (0.38) | FABP3FABP4METAP2DHODHADORA1 | |
| SCHEMBL14600486 | 0.84 | PDE4B (0.43) | FABP3FABP4ADORA1PDE4BTP53 | |
| SCHEMBL14600669 | 0.83 | DHODH (0.38) | FABP3FABP4METAP2DHODHADORA1 | |
| SCHEMBL4665751 | 0.83 | HPGD (0.43) | TP53MAPTLMNA | |
| SCHEMBL14600213 | 0.83 | ADORA1 (0.39) | FABP3FABP4METAP2DHODHADORA1 | |
| SCHEMBL14600226 | 0.81 | ALDH1A1 (0.40) | FABP3FABP4ADORA1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |