Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 7/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668570 | 0.94 | GFER (0.42) | PDE4BFTOADORA1GFERMAPT | |
| Hydrochloric Acid SCHEMBL4669539 | 0.93 | GFER (0.41) | PDE4BFTOADORA1GFERMAPT | |
| SCHEMBL14600686 | 0.86 | FTO (0.40) | PDE4BFTOGFERMAPTTP53 | |
| SCHEMBL4665751 | 0.86 | HPGD (0.43) | GFERMAPTTP53MEN1LMNA | |
| SCHEMBL14600681 | 0.85 | DHODH (0.44) | PDE4BFTOGFERMAPTTP53 | |
| SCHEMBL14600476 | 0.84 | KDM4C (0.43) | ADORA2BADORA1GFERMAPTTP53 | |
| SCHEMBL4668419 | 0.84 | FABP3 (0.39) | PDE4BADORA1MAPTTP53LMNA | |
| SCHEMBL14600271 | 0.83 | GRM5 (0.49) | FTOGFERMAPTMEN1LMNA | |
| SCHEMBL4666522 | 0.83 | KDM4C (0.43) | FTOADORA2BADORA1GFERMAPT | |
| SCHEMBL14600270 | 0.81 | GFER (0.42) | FTOADORA1GFERMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |