SCHEMBL4668585

SCHEMBL4668585

CCCCCCCCc1cc2cccc3c2c(c1-c1cccc2cc4ccccc4cc12)-c1c-3ccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.37
ESR2 Q92731 6/20 0.37
DHFR P00374 1/20 0.36
TLR8 Q9NR97 4/20 0.36
GCGR P47871 2/20 0.33
CNR1 P21554 2/20 0.33
CES1 P23141 1/20 0.33
GPR3 P46089 1/20 0.33
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
APAF1 O14727 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2140658 0.89 DHFR (0.38) ESR1ESR2DHFRTLR8GCGR
SCHEMBL27680873 0.80 CES1 (0.42) ESR1ESR2CES1MAPTKDM4E
SCHEMBL28057881 0.73 ESR1 (0.47) ESR1ESR2DHFRTLR8GCGR
SCHEMBL4667935 0.73 CES1 (0.40) ESR1ESR2CES1MAPTKDM4E
SCHEMBL5008901 0.72 TLR8 (0.43) TLR8GCGRCNR1GPR3MAPT
SCHEMBL6058867 0.71 ESR1 (0.42) ESR1ESR2DHFRTLR8GCGR
SCHEMBL16796020 0.71 TLR8 (0.44) TLR8GCGRCNR1GPR3ALDH1A1
SCHEMBL15229930 0.71 ESR1 (0.41) ESR1ESR2DHFRTLR8GCGR
SCHEMBL16896253 0.71 ESR1 (0.41) ESR1ESR2DHFRTLR8GCGR
SCHEMBL6058865 0.71 TLR8 (0.43) TLR8CNR1GPR3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1920478-A2 WHITE ORGANIC ILLUMINATING DIODES (OLEDS) BASED ON EXCIPLEX DOUBLE BLUE FLUORESCENT COMPOUNDS BASF SE (DE) 2008-05-14 EP claimed
WO-2007039344-A2 WHITE ORGANIC ILLUMINATING DIODES (OLEDS) BASED ON EXCIPLEX DOUBLE BLUE FLUORESCENT COMPOUNDS BASF SE (DE) 2007-04-12 WO claimed