Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16796020 | 0.99 | TLR8 (0.44) | TLR8GPR3NR1H2NR1H3LIPG | |
| SCHEMBL11693719 | 0.94 | TLR8 (0.43) | TLR8ELANECTSGALDH1A1TP53 | |
| SCHEMBL11689514 | 0.85 | ALDH1A1 (0.40) | TLR8ELANECTSGGCGRALDH1A1 | |
| SCHEMBL27684805 | 0.82 | ELANE (0.42) | TLR8GPR3NR1H2NR1H3LIPG | |
| SCHEMBL5010999 | 0.82 | TLR8 (0.41) | TLR8NR1H2NR1H3LIPGCNR1 | |
| SCHEMBL19371898 | 0.82 | TLR8 (0.43) | TLR8GPR3NR1H2NR1H3LIPG | |
| SCHEMBL28676696 | 0.81 | ALDH1A1 (0.42) | TLR8GPR3NR1H2NR1H3LIPG | |
| SCHEMBL11229645 | 0.78 | TLR8 (0.59) | TLR8GPR3NR1H2NR1H3LIPG | |
| SCHEMBL11227235 | 0.78 | TLR8 (0.59) | TLR8GPR3NR1H2NR1H3LIPG | |
| SCHEMBL20656619 | 0.77 | ELANE (0.45) | TLR8GPR3NR1H2NR1H3LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |