Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3001927 | 0.86 | UGT2B7 (0.61) | UGT2B7ADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL2846227 | 0.81 | LMNA (0.50) | TDP1 | |
| SCHEMBL9812362 | 0.79 | ACP3 (0.52) | — | |
| SCHEMBL28054154 | 0.79 | ACP3 (0.52) | — | |
| SCHEMBL11020997 | 0.79 | TYR (0.56) | CYP1A2UGT2B7ADRA2AADRA2BADRA2C | |
| Ammonia Solution, Strong SCHEMBL10808062 | 0.79 | LMNA (0.48) | TDP1 | |
| SCHEMBL4669037 | 0.78 | AKR1C3 (0.58) | CYP2A6TDP1CYP1A2 | |
| SCHEMBL16192437 | 0.78 | ACHE (0.46) | TDP1 | |
| SCHEMBL30253980 | 0.77 | CYP2A6 (0.62) | CYP2A6TDP1CYP1A2UGT2B7SLC6A2 | |
| SCHEMBL11508362 | 0.77 | ESR1 (0.42) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221369-A1 | Process for the preparation of substituted phenols | DAICEL CHEMICAL INSDUSTRIES, LTD. (JP) | 2008-09-11 | — | — | US | disclosed |
| EP-1967505-A1 | Process for the preparation of substituted phenols | Daicel Chemical Industries, Ltd. (JP) | 2008-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221369-A1 | Process for the preparation of substituted phenols | CYP1A1, NOX1, ROS1 | CYP2A6 109/4885TDP1 2885/4885CYP1A2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.