Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8643448 | 0.83 | ESR1 (0.55) | ALDH1A1KDM4EKMT2AESR1PDCD1 | |
| SCHEMBL5109088 | 0.80 | KDM4E (0.49) | ALDH1A1KDM4ESLC6A4MEN1KMT2A | |
| SCHEMBL14033851 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4ESLC6A4MEN1KMT2A | |
| SCHEMBL7499823 | 0.80 | TAAR1 (0.50) | ALDH1A1KDM4EKMT2AESR1PDCD1 | |
| Benzene SCHEMBL28192760 | 0.80 | TAAR1 (0.50) | ALDH1A1KDM4EKMT2AESR1PDCD1 | |
| SCHEMBL169730 | 0.80 | TAAR1 (0.50) | ALDH1A1KDM4EKMT2AESR1PDCD1 | |
| SCHEMBL1345040 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4ESLC6A4MEN1KMT2A | |
| Ethane SCHEMBL11274743 | 0.77 | TAAR1 (0.48) | ALDH1A1KDM4EKMT2AESR1PDCD1 | |
| Hydrogen Peroxide SCHEMBL8846644 | 0.77 | ESR1 (0.55) | ALDH1A1KDM4EMEN1KMT2ACYP3A4 | |
| Bromide SCHEMBL2016300 | 0.77 | TAAR1 (0.48) | ALDH1A1KDM4EKMT2AESR1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221369-A1 | Process for the preparation of substituted phenols | DAICEL CHEMICAL INSDUSTRIES, LTD. (JP) | 2008-09-11 | — | — | US | disclosed |
| EP-1967505-A1 | Process for the preparation of substituted phenols | Daicel Chemical Industries, Ltd. (JP) | 2008-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221369-A1 | Process for the preparation of substituted phenols | CYP1A1, NOX1, ROS1 | ALDH1A1 308/4885KDM4E 418/4885SLC6A4 3928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.