Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320342 | 0.91 | ESR1 (0.48) | TSHRHSD17B10CYP3A4ALOX15ADRA2C | |
| SCHEMBL1008910 | 0.84 | ALDH1A1 (0.56) | TSHRHSD17B10CYP3A4ALOX15ALOX12 | |
| SCHEMBL14283585 | 0.84 | TSHR (0.59) | TSHRHSD17B10HTR2ATAAR1CYP3A4 | |
| SCHEMBL9321260 | 0.84 | TSHR (0.59) | TSHRHSD17B10HTR2ATAAR1CYP3A4 | |
| SCHEMBL13975687 | 0.84 | ALDH1A1 (0.56) | TSHRHSD17B10CYP3A4ALOX15ALOX12 | |
| SCHEMBL8643448 | 0.83 | ESR1 (0.55) | TSHRTAAR1CYP2D6ADRA2CESR1 | |
| SCHEMBL19682009 | 0.82 | ESR1 (0.41) | TSHRHSD17B10ESR1PDCD1ESR2 | |
| SCHEMBL4547310 | 0.82 | ALDH1A1 (0.59) | TSHRHSD17B10CYP3A4ALOX15ALOX12 | |
| SCHEMBL11093676 | 0.80 | TSHR (0.54) | TSHRHSD17B10HTR2ACYP3A4ALOX15 | |
| SCHEMBL169730 | 0.80 | TAAR1 (0.50) | TSHRTAAR1CYP2D6ADRA2CESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221369-A1 | Process for the preparation of substituted phenols | DAICEL CHEMICAL INSDUSTRIES, LTD. (JP) | 2008-09-11 | — | — | US | disclosed |
| EP-1967505-A1 | Process for the preparation of substituted phenols | Daicel Chemical Industries, Ltd. (JP) | 2008-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221369-A1 | Process for the preparation of substituted phenols | CYP1A1, NOX1, ROS1 | TSHR 3848/4885HSD17B10 647/4885HTR2A 1122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.