SCHEMBL4547310

SCHEMBL4547310

CC(c1ccccc1)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.59
HSD17B10 Q99714 6/20 0.59
ALOX12 P18054 5/20 0.59
CYP3A4 P08684 5/20 0.59
TSHR P16473 4/20 0.59
L3MBTL1 Q9Y468 4/20 0.59
TDP1 Q9NUW8 4/20 0.59
ALOX15 P16050 3/20 0.59
LMNA P02545 2/20 0.59
THRB P10828 1/20 0.59
RECQL P46063 1/20 0.59
ATM Q13315 1/20 0.59
MAPK1 P28482 2/20 0.59
PTGS1 P23219 1/20 0.59
SLC6A2 P23975 1/20 0.59
PTGS2 P35354 1/20 0.59
HTR2B P41595 1/20 0.59
HPGD P15428 4/20 0.54
MAPT P10636 5/20 0.50
CYP26A1 O43174 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13975687 0.98 ALDH1A1 (0.56) ALDH1A1HSD17B10ALOX12CYP3A4TSHR
SCHEMBL1008910 0.98 ALDH1A1 (0.56) ALDH1A1HSD17B10ALOX12CYP3A4TSHR
SCHEMBL15960970 0.90 HPGD (0.65) ALDH1A1HSD17B10ALOX12CYP3A4TSHR
SCHEMBL26176821 0.90 PTGS2 (0.50) ALDH1A1HSD17B10ALOX12CYP3A4TSHR
SCHEMBL10781589 0.87 HPGD (0.68) ALDH1A1HSD17B10ALOX12CYP3A4TSHR
SCHEMBL10938387 0.86 ALDH1A1 (0.46) ALDH1A1HSD17B10ALOX12CYP3A4TSHR
SCHEMBL9782628 0.85 ALDH1A1 (0.54) ALDH1A1HSD17B10ALOX12CYP3A4TSHR
SCHEMBL2749867 0.84 ALDH1A1 (0.62) ALDH1A1HSD17B10ALOX12CYP3A4TSHR
SCHEMBL8643448 0.83 ESR1 (0.55) ALDH1A1TSHRLMNAKMT2AHIF1A
SCHEMBL4668638 0.82 TSHR (0.56) ALDH1A1HSD17B10ALOX12CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689843-B2 CONTAINING AN AROMATIC SECONDARY AMINE COMPOUND AND A NICKEL DIALKYLDITHIOCARBAMATE; OPTIONALLY A DIAMINE CROSSLINKING AGENT ZEON CORPORATION (JP) 2004-02-10 US claimed
US-20030027935-A1 Acrylic rubber composition, crosslinkable acrylic rubber composition, and crosslinked object obtained therefrom ZEON CORPORATION (JP) 2003-02-06 US claimed
EP-1270666-A1 ACRYLIC RUBBER COMPOSITION, CROSSLINKABLE ACRYLIC RUBBER COMPOSITION, AND CROSSLINKED OBJECT OBTAINED THEREFROM Zeon Corporation (JP) 2003-01-02 EP claimed
WO-2024122352-A1 POLYMER FILM, LAMINATE AND METALLIZED LAMINATE 富士フイルム株式会社 2024-06-13 WO disclosed
EP-4130131-A1 ACRYLIC RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT Zeon Corporation (JP) 2023-02-08 EP disclosed
EP-3992236-A1 ACRYLIC RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT Zeon Corporation (JP) 2022-05-04 EP disclosed
EP-3992218-A1 ACRYLIC RUBBER, ACRYLIC RUBBER COMPOSITION, AND CROSSLINKED RUBBER Zeon Corporation (JP) 2022-05-04 EP disclosed
US-20190276634-A1 ACRYLIC POLYMER COMPOSITION ZEON CORPORATION (JP) 2019-09-12 US disclosed
US-20190112467-A1 ACRYLIC POLYMER COMPOSITION ZEON CORPORATION (JP) 2019-04-18 US disclosed
US-20190112466-A1 ACRYLIC POLYMER COMPOSITION ZEON CORPORATION (JP) 2019-04-18 US disclosed
US-20190106552-A1 ACRYLIC POLYMER COMPOSITION ZEON CORPORATION (JP) 2019-04-11 US disclosed
US-20090270289-A1 Phosphorus-molybdenum compound, method for producing same and lubricant additive and lubricant composition containing the compound ADEKA CORPORATION (JP) 2009-10-29 US disclosed
US-20080274925-A1 Alkylated Pana and Dpa Compositions CIBA SPECIALTY CHEMICALS CORP. 2008-11-06 US disclosed
US-20080274925-A1 Alkylated Pana and Dpa Compositions CIBA SPECIALTY CHEMICALS CORP. 2008-11-06 US disclosed
US-20080071014-A1 Acrylic Rubber Composition And Acrylic Rubber Vulcanizate ZEON CORPORATION (JP) 2008-03-20 US disclosed
US-20080071014-A1 Acrylic Rubber Composition And Acrylic Rubber Vulcanizate ZEON CORPORATION (JP) 2008-03-20 US disclosed
EP-1790689-A1 ACRYLIC RUBBER COMPOSITION AND ACRYLIC RUBBER CROSSLINKED PRODUCT ZEON CORPORATION (JP) 2007-05-30 EP disclosed
US-6689843-B2 CONTAINING AN AROMATIC SECONDARY AMINE COMPOUND AND A NICKEL DIALKYLDITHIOCARBAMATE; OPTIONALLY A DIAMINE CROSSLINKING AGENT ZEON CORPORATION (JP) 2004-02-10 US disclosed
US-20030027935-A1 Acrylic rubber composition, crosslinkable acrylic rubber composition, and crosslinked object obtained therefrom ZEON CORPORATION (JP) 2003-02-06 US disclosed
EP-1270666-A1 ACRYLIC RUBBER COMPOSITION, CROSSLINKABLE ACRYLIC RUBBER COMPOSITION, AND CROSSLINKED OBJECT OBTAINED THEREFROM Zeon Corporation (JP) 2003-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270289-A1 Phosphorus-molybdenum compound, method for producing same and lubricant additive and lubricant composition containing the compound JAK1, PRDX1, PRDX4 ALDH1A1 3010/4885HSD17B10 1172/4885ALOX12 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.