Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.55 |
| ▸ | ATF4 | P18848 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668785 | 1.00 | MCHR1 (0.55) | MCHR1ATF4POLBKCNH2 | |
| SCHEMBL3869032 | 0.97 | MCHR1 (0.51) | MCHR1ATF4POLB | |
| SCHEMBL3869029 | 0.97 | MCHR1 (0.51) | MCHR1ATF4POLB | |
| SCHEMBL3872107 | 0.92 | MCHR1 (0.61) | MCHR1ATF4POLBKCNH2 | |
| SCHEMBL3872106 | 0.92 | MCHR1 (0.61) | MCHR1ATF4POLBKCNH2 | |
| SCHEMBL3869587 | 0.84 | ATF4 (0.66) | ATF4POLB | |
| SCHEMBL3869586 | 0.84 | ATF4 (0.66) | ATF4POLB | |
| SCHEMBL3870007 | 0.79 | L3MBTL1 (0.48) | MCHR1ATF4 | |
| SCHEMBL3870004 | 0.79 | L3MBTL1 (0.48) | MCHR1ATF4 | |
| SCHEMBL3872069 | 0.77 | EPHX2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891064-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | Laboratorios Almirall, S.A. (ES) | 2008-02-27 | — | — | EP | claimed |
| WO-2006133802-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-12-21 | — | — | WO | claimed |
| EP-1891064-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | Laboratorios Almirall, S.A. (ES) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006133802-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-12-21 | — | — | WO | disclosed |