Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.54 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746902 | 0.82 | PHGDH (0.37) | CNR1CNR2 | |
| SCHEMBL14205956 | 0.81 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL5057268 | 0.81 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL14043684 | 0.80 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL5576871 | 0.78 | CNR1 (0.69) | CNR1CNR2SMN1; SMN2 | |
| SCHEMBL4671450 | 0.77 | LMNA (0.47) | CNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5057212 | 0.77 | CNR1 (0.73) | CNR1CNR2 | |
| SCHEMBL14043954 | 0.77 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL5058668 | 0.76 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL14206245 | 0.76 | CNR1 (0.65) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937677-A1 | CB-1 MODULATING COMPOUNDS AND THEIR USE | Arcadia Pharmaceuticals Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007047737-A1 | CB-1 MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2007-04-26 | — | — | WO | disclosed |