Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 9/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668903 | 0.82 | CNR1 (0.54) | CNR1CNR2 | |
| SCHEMBL4746911 | 0.81 | CNR1 (0.48) | PHGDHCNR1CNR2MEN1APAF1 | |
| SCHEMBL4748158 | 0.68 | PTGDR2 (0.34) | CNR1HRH4 | |
| SCHEMBL4855914 | 0.67 | GPR119 (0.33) | CNR1 | |
| SCHEMBL5576871 | 0.66 | CNR1 (0.69) | CNR1CNR2ALDH1A1GAAMAPT | |
| SCHEMBL4671450 | 0.64 | LMNA (0.47) | CNR1ALDH1A1MAPTHTT | |
| SCHEMBL5057268 | 0.63 | CNR1 (0.66) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL14205956 | 0.63 | CNR1 (0.66) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL4669165 | 0.62 | MEN1 (0.51) | MEN1ALDH1A1MAPTKMT2AHTR2C | |
| SCHEMBL14043684 | 0.62 | CNR1 (0.65) | CNR1CNR2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118141-A2 | USE OF CANNABINOID MODULATING COMPOUNDS IN COMBINATION WITH OTHER THERAPEUTIC COMPOUNDS FOR ADJUNCTIVE THERAPY | ACADIA PHARMACEUTICALS INC. (US) | 2008-10-02 | — | — | WO | disclosed |