SCHEMBL4669012

SCHEMBL4669012

O=Cc1cccn1-c1cccc(Cl)c1Cl

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.51
KMT2A Q03164 2/20 0.49
ATM Q13315 1/20 0.49
ALDH1A1 P00352 6/20 0.41
POLB P06746 1/20 0.41
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
MEN1 O00255 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HCAR1 Q9BXC0 1/20 0.39
CYP1A2 P05177 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
DRD2 P14416 2/20 0.38
DRD3 P35462 2/20 0.38
ADRB1 P08588 1/20 0.38
CYP11B2 P19099 1/20 0.35
NOTUM Q6P988 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL950144 0.80 ATM (0.53) GAAKMT2AATMALDH1A1POLB
SCHEMBL951077 0.78 GAA (0.50) GAAKMT2AATMALDH1A1POLB
SCHEMBL7014514 0.75 NOTUM (0.46) GAAKMT2AATMALDH1A1POLB
SCHEMBL950454 0.73 ALDH1A1 (0.46) GAAATMALDH1A1POLBTRIM24
SCHEMBL950321 0.72 ALDH1A1 (0.45) GAAKMT2AATMALDH1A1POLB
SCHEMBL7015178 0.72 GAA (0.48) GAAKMT2AATMALDH1A1POLB
SCHEMBL1321565 0.71 GAA (0.58) GAAKMT2AATMALDH1A1POLB
SCHEMBL5972069 0.71 GAA (0.58) GAAKMT2AATMALDH1A1POLB
SCHEMBL32680206 0.70 P2RX7 (0.45) KMT2AALDH1A1MEN1TDP1HCAR1
SCHEMBL6417731 0.69 ATM (0.63) GAAKMT2AATMALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed