Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LTC4S | Q16873 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670961 | 0.87 | MEN1 (0.32) | POLBPKMALDH1A1MEN1KMT2A | |
| SCHEMBL4824088 | 0.69 | MEN1 (0.39) | POLBPKMLTC4SALDH1A1MEN1 | |
| SCHEMBL4669089 | 0.68 | POLB (0.35) | POLBALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL4670894 | 0.67 | POLB (0.34) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4824084 | 0.67 | KMT2A (0.38) | LTC4SALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4672795 | 0.65 | MEN1 (0.34) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16586215 | 0.64 | NAPRT (0.44) | POLBPKMALDH1A1MEN1KMT2A | |
| SCHEMBL9563445 | 0.63 | NAPRT (0.43) | POLBPKMALDH1A1MEN1KMT2A | |
| SCHEMBL5209363 | 0.62 | MAPT (0.40) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16586010 | 0.62 | DGAT1 (0.47) | POLBPKMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757586-B1 | POLYSBUSTITUIRTE 1,1-PYRIDINYLAMINOCYCLOPROPANAMIN DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE ENTHALTENDE PHARMATUETISCHE ZUSAMMENSETZUNG | SERVIER LAB (FR) | 2008-12-03 | — | — | EP | disclosed |
| EP-1757586-A1 | POLYSBUSTITUIRTE 1,1-PYRIDINYLAMINOCYCLOPROPANAMIN DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE ENTHALTENDE PHARMATUETISCHE ZUSAMMENSETZUNG | Les Laboratoires Servier (FR) | 2007-02-28 | — | — | EP | disclosed |