Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3916724 | 0.91 | TDP1 (0.37) | PPARGPPARDPPARATSHRGPR84 | |
| SCHEMBL16860500 | 0.80 | CES2 (0.45) | CES2PPARGPPARDPPARATSHR | |
| SCHEMBL11817654 | 0.80 | CES2 (0.45) | CES2PPARGPPARDPPARATSHR | |
| SCHEMBL6001993 | 0.80 | CES2 (0.45) | CES2PPARGPPARDPPARATSHR | |
| SCHEMBL10736732 | 0.80 | CES2 (0.45) | CES2PPARGPPARDPPARATSHR | |
| SCHEMBL10998086 | 0.80 | CES2 (0.45) | CES2PPARGPPARDPPARATSHR | |
| SCHEMBL29196171 | 0.80 | CES2 (0.45) | CES2PPARGPPARDPPARATSHR | |
| SCHEMBL22264633 | 0.80 | CES2 (0.45) | CES2PPARGPPARDPPARATSHR | |
| SCHEMBL22264627 | 0.80 | CES2 (0.45) | CES2PPARGPPARDPPARATSHR | |
| SCHEMBL27520410 | 0.80 | PPARD (0.47) | CES2PPARGPPARDPPARATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902146-A2 | METHODS FOR IDENTIFYING PHARMACOLOGY AND TOXICOLOGY | Ribonomics, Inc. (US) | 2008-03-26 | — | — | EP | claimed |
| WO-2007050132-A2 | METHODS FOR IDENTIFYING PHARMACOLOGY AND TOXICOLOGY | RIBONOMICS, INC. (US) | 2007-05-03 | — | — | WO | claimed |
| US-20060275816-A1 | Methods for identifying drug pharmacology and toxicology | RIBONOMICS, INC. (US) | 2006-12-07 | — | — | US | claimed |
| EP-1902146-A2 | METHODS FOR IDENTIFYING PHARMACOLOGY AND TOXICOLOGY | Ribonomics, Inc. (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007050132-A2 | METHODS FOR IDENTIFYING PHARMACOLOGY AND TOXICOLOGY | RIBONOMICS, INC. (US) | 2007-05-03 | — | — | WO | disclosed |
| US-20060275816-A1 | Methods for identifying drug pharmacology and toxicology | RIBONOMICS, INC. (US) | 2006-12-07 | — | — | US | disclosed |