Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669044 | 0.91 | FDPS (0.45) | TDP1KMT2AALDH1A1PPARGPPARD | |
| SCHEMBL1225614 | 0.78 | AKR1B1 (0.39) | TDP1KMT2AAKR1B1ALDH1A1PPARG | |
| SCHEMBL6003058 | 0.78 | AKR1B1 (0.39) | TDP1KMT2AAKR1B1ALDH1A1PPARG | |
| SCHEMBL11755736 | 0.78 | AKR1B1 (0.39) | TDP1KMT2AAKR1B1ALDH1A1PPARG | |
| SCHEMBL605019 | 0.75 | TSHR (0.43) | TDP1KMT2AAKR1B1ALDH1A1PPARG | |
| SCHEMBL249872 | 0.75 | ACLY (0.56) | TDP1AKR1B1ALDH1A1PPARGPPARA | |
| SCHEMBL2103333 | 0.75 | TSHR (0.43) | TDP1KMT2AAKR1B1ALDH1A1PPARG | |
| SCHEMBL380384 | 0.75 | TDP1 (0.46) | TDP1KMT2AL3MBTL1AKR1B1ALDH1A1 | |
| SCHEMBL636456 | 0.75 | AKR1B1 (0.40) | TDP1KMT2AAKR1B1ALDH1A1PPARG | |
| SCHEMBL381209 | 0.75 | TSHR (0.43) | TDP1KMT2AAKR1B1ALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1843760-A4 | CLASSES OF COMPOUNDS THAT INTERACT WITH INTEGRINS | ALCHEMIA LTD (AU) | 2009-03-25 | — | — | EP | disclosed |
| EP-1843760-A1 | CLASSES OF COMPOUNDS THAT INTERACT WITH INTEGRINS | Alchemia Pty Ltd (AU) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006081616-A1 | CLASSES OF COMPOUNDS THAT INTERACT WITH INTEGRINS | ALCHEMIA LIMITED (AU) | 2006-08-10 | — | — | WO | disclosed |