Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669101 | 0.93 | CHRNB2 (0.57) | CHRNB2CHRNA4PPARGPPARASLC6A4 | |
| SCHEMBL10974760 | 0.85 | CHRNB2 (0.53) | CHRNB2CHRNA4PPARGPPARASLC6A4 | |
| SCHEMBL10965877 | 0.82 | CHRNB2 (0.50) | CHRNB2CHRNA4PPARGPPARASLC6A4 | |
| SCHEMBL10969378 | 0.80 | SIGMAR1 (0.56) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL10966028 | 0.78 | SIGMAR1 (0.49) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL4057684 | 0.77 | CHRM3 (0.55) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL4064509 | 0.77 | CHRM3 (0.55) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL4060176 | 0.77 | CHRM3 (0.55) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL7962794 | 0.76 | SLC6A4 (0.39) | CHRNB2CHRNA4SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11953999 | 0.76 | CHRNB2 (0.42) | CHRNB2CHRNA4SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930308-A1 | Pharmaceutical agents for the treatment of cerebral amyloidosis | NYMOX CORPORATION (CA) | 2008-06-11 | — | — | EP | disclosed |