Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 3/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | THPO | P40225 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983440 | 0.94 | SCN1A (0.52) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL21861456 | 0.92 | SCN1A (0.50) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL6978977 | 0.92 | SCN1A (0.50) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL6981112 | 0.92 | SCN1A (0.50) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL2017633 | 0.87 | CHRM2 (0.57) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL4669231 | 0.87 | SLC6A2 (0.61) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL4670218 | 0.87 | SCN1A (0.61) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL4667564 | 0.82 | SCN1A (0.65) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL8746929 | 0.80 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3LMNAKCNH2 | |
| SCHEMBL6768989 | 0.80 | ALDH1A1 (0.41) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243905-B1 | 1-(omega-[bis-(phenyl)alkoxy]-alkyl)-4-(di-(phenyl)-methyl)piperazines, process for their preparation and medicines containing them | RICHTER GEDEON VEGYESZET (HU) | 1990-10-10 | — | — | EP | disclosed |
| US-4868184-A | DISEASES ARISING FROM LOW DOPAMINE LEVEL; ANTIDEPRESSANTS; PARKINSON'S DISEASE; NERVOUS SYSTEM, GLANDULAR AND UROGENITAL SYSTEM DISORDERS | RICHTER GEDEON VEGYESZETI GYAR (HU) | 1989-09-19 | — | — | US | disclosed |
| EP-0243905-A1 | 1-(omega-[bis-(phenyl)alkoxy]-alkyl)-4-(di-(phenyl)-methyl)piperazines, process for their preparation and medicines containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-11-04 | — | — | EP | disclosed |
| US-4673684-A | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient | TERUMO CORPORATION (JP) | 1987-06-16 | — | — | US | disclosed |
| EP-0157420-A2 | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1985-10-09 | — | — | EP | disclosed |