Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 3/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | THPO | P40225 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288351 | 0.87 | SCN1A (0.57) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL4670218 | 0.87 | SCN1A (0.61) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL4669231 | 0.87 | SLC6A2 (0.61) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL16767874 | 0.83 | HRH1 (0.52) | SLC6A4SLC6A3HTR2AHRH1CYP1A2 | |
| SCHEMBL4667564 | 0.82 | SCN1A (0.65) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| Bromomethane SCHEMBL5569429 | 0.82 | SLC6A2 (0.56) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL7978015 | 0.81 | SIGMAR1 (0.67) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL891208 | 0.80 | HRH1 (0.48) | SLC6A4SLC6A3HTR2AHRH1CYP1A2 | |
| SCHEMBL7263992 | 0.80 | CHRNB2 (0.51) | HTR2AHRH1 | |
| SCHEMBL4667514 | 0.79 | SCN1A (0.53) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150174264-A1 | Oligomer-Antihistamine Conjugates | NEKTAR THERAPEUTICS (US) | 2015-06-25 | — | — | US | disclosed |
| US-20100152201-A1 | Oligomer-Antihistamine Conjugates | NEKTAR THERAPEUTICS (US) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174264-A1 | Oligomer-Antihistamine Conjugates | HRH4, HRH1, HRH3 | SCN1A 3216/4885SCN2A 3338/4885SCN3A 2507/4885 |
| US-20100152201-A1 | Oligomer-Antihistamine Conjugates | HRH4, HRH1, HRH3 | SCN1A 3372/4885SCN2A 3555/4885SCN3A 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.