Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669427 | 1.00 | LMNA (0.42) | LMNAGAASMN1; SMN2TDP1CASP6 | |
| SCHEMBL13068354 | 0.87 | LMNA (0.46) | LMNAGAASMN1; SMN2TDP1CASP6 | |
| SCHEMBL3826933 | 0.87 | LMNA (0.46) | LMNAGAASMN1; SMN2TDP1CASP6 | |
| SCHEMBL3826925 | 0.87 | LMNA (0.46) | LMNAGAASMN1; SMN2TDP1CASP6 | |
| SCHEMBL2492792 | 0.79 | LMNA (0.47) | LMNAGAASMN1; SMN2TDP1CASP6 | |
| SCHEMBL1737650 | 0.78 | LMNA (0.48) | LMNASMN1; SMN2TDP1MAPTBLM | |
| SCHEMBL28129585 | 0.78 | LMNA (0.48) | LMNASMN1; SMN2TDP1MAPTBLM | |
| SCHEMBL1737652 | 0.78 | LMNA (0.48) | LMNASMN1; SMN2TDP1MAPTBLM | |
| SCHEMBL14501956 | 0.77 | LMNA (0.41) | LMNASMN1; SMN2TDP1CASP6L3MBTL1 | |
| SCHEMBL1231766 | 0.76 | LMNA (0.55) | LMNATDP1CASP6L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930338-A1 | Fumaric acid derivates and ophtalmic lenses using the same | E-brain Corporation Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |