Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | CA9 | Q16790 | 5/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.62 |
| ▸ | CA7 | P43166 | 4/20 | 0.62 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742350 | 0.89 | CA1 (0.69) | CA1CA2CA9CA14CA7 | |
| SCHEMBL5522656 | 0.83 | GID4 (0.69) | CA1CA2CA9CA14CA7 | |
| SCHEMBL5523066 | 0.82 | CA1 (0.57) | CA1CA2CA9CA14CA7 | |
| SCHEMBL4674453 | 0.82 | KMT2A (0.71) | CA1CA2CA9CA14CA7 | |
| SCHEMBL4242796 | 0.82 | CA1 (0.60) | CA1CA2CA9CA14CA7 | |
| SCHEMBL29670244 | 0.82 | CA1 (0.70) | CA1CA2CA9CA14CA7 | |
| SCHEMBL19453945 | 0.82 | CA1 (0.70) | CA1CA2CA9CA14CA7 | |
| SCHEMBL4244900 | 0.82 | CA1 (0.54) | CA1CA2CA9CA14CA7 | |
| SCHEMBL6716383 | 0.81 | CA1 (0.69) | CA1CA2CA9CA14CA7 | |
| SCHEMBL6715368 | 0.81 | CA1 (0.69) | CA1CA2CA9CA14CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732898-B1 | TETRAHYDROISOQUINOLINE- AND TETRAHYDROBENZAZEPINE DERIVATIVES AS IGF-1R INHIBITORS | ANALYTECON SA (CH) | 2008-01-23 | — | — | EP | disclosed |