Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235823 | 0.90 | CA1 (0.54) | CA1CA2CA9CA14CA7 | |
| SCHEMBL4239697 | 0.89 | CA1 (0.53) | CA1CA2CA9CA14CA7 | |
| SCHEMBL5523066 | 0.86 | CA1 (0.57) | CA1CA2CA9CA14CA7 | |
| SCHEMBL4669532 | 0.82 | CA1 (0.62) | CA1CA2CA9CA14CA7 | |
| SCHEMBL4241492 | 0.79 | CA1 (0.53) | CA1CA2CA9CA14CA7 | |
| SCHEMBL28742350 | 0.79 | CA1 (0.69) | CA1CA2CA9CA14CA7 | |
| SCHEMBL4674453 | 0.75 | KMT2A (0.71) | CA1CA2CA9CA14CA7 | |
| SCHEMBL4242796 | 0.75 | CA1 (0.60) | CA1CA2CA9CA14CA7 | |
| SCHEMBL5513461 | 0.74 | CA1 (0.58) | CA1CA2CA9CA14CA7 | |
| SCHEMBL5520356 | 0.74 | CA1 (0.58) | CA1CA2CA9CA14CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099133-A1 | Isoquinolines Derivatives as Igf-1R Inhibitors | ANALYTECON S.A. (CH) | 2009-04-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099133-A1 | Isoquinolines Derivatives as Igf-1R Inhibitors | IGF1R, IGFBP1, IGF2BP1 | CA1 4832/4885CA2 4798/4885CA9 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.