Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.55 |
| ▸ | FDPS | P14324 | 6/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499300 | 0.87 | SMPD1 (0.48) | SMPD1FDPSPTPN1LPAR3LPAR1 | |
| SCHEMBL27759001 | 0.86 | SMPD1 (0.48) | SMPD1FDPSLAP3S1PR2S1PR1 | |
| SCHEMBL29288454 | 0.84 | FDPS (0.45) | SMPD1FDPSPTPN1LAP3S1PR2 | |
| SCHEMBL4669700 | 0.83 | CYP3A4 (0.44) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL27727331 | 0.81 | FDPS (0.42) | SMPD1FDPSLAP3S1PR2S1PR1 | |
| SCHEMBL1923648 | 0.78 | SMPD1 (0.59) | SMPD1FDPSPTPN1LPAR3LPAR1 | |
| SCHEMBL1477860 | 0.78 | — | — | |
| SCHEMBL28189880 | 0.77 | PLA2G2C (0.40) | SMPD1FDPSPTPN1LPAR3LPAR1 | |
| SCHEMBL27748409 | 0.77 | FDPS (0.39) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL3010735 | 0.77 | SMPD1 (0.57) | SMPD1FDPSPTPN1LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114288760-B | Fuel cell cathode air filtering adsorption filter material and application thereof | 广州华创化工材料科技开发有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-114288760-A | Fuel cell cathode air filtering adsorption filter material and application thereof | 广州华创化工材料科技开发有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-104689849-A | Phosphamide-(di) secondary amine dual-functional catalyst and synthesis method thereof | UNIV EAST CHINA NORMAL | 2015-06-10 | — | — | CN | claimed |
| CN-102040630-A | Preparation method of three-in-one acrylic acid phosphoric melamine expansion flame retardant oligomer | UNIV NANCHANG HANGKONG | 2011-05-04 | — | — | CN | claimed |
| CN-117364487-B | Preparation method of durable flame-retardant coating polyester/cotton blended fabric | 江苏恒力化纤股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117364487-A | Preparation method of durable flame-retardant coating polyester/cotton blended fabric | 江苏恒力化纤股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| WO-2023102529-A1 | THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION | GILEAD SCIENCES, INC. (US) | 2023-06-08 | — | — | WO | disclosed |
| CN-115109420-A | Flame-retardant polyvinyl alcohol modified composition and preparation method thereof | 电子科技大学中山学院 | 2022-09-27 | — | — | CN | disclosed |
| CN-114288760-B | Fuel cell cathode air filtering adsorption filter material and application thereof | 广州华创化工材料科技开发有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114288760-A | Fuel cell cathode air filtering adsorption filter material and application thereof | 广州华创化工材料科技开发有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-114196002-A | Preparation method of transparent flame-retardant novel polycarbonate, polycarbonate and application thereof | 万华化学（宁波）有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-111925728-A | Modified epoxy resin powder coating with high adhesive force | 何瑞坚 | 2020-11-13 | — | — | CN | disclosed |
| US-6448401-B1 | REACTING A TRIAZOLE ANTIFUNGAL COMPOUND CONTAINING A SECONDARY OR TERTIARY HYDROXYL GROUP WITH A PROTECTED MONOCHLOROMETHYL PHOSPHATE; IODIDE ION SOURCE; ORGANIC SOLVENT; BASE | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-10 | — | — | US | disclosed |
| WO-2002042283-A1 | IMPROVED PROCESS FOR WATER SOLUBLE AZOLE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-05-30 | — | — | WO | disclosed |
| US-20020062028-A1 | Process for water soluble azole compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2002-05-23 | — | — | US | disclosed |
| US-6362172-B2 | (DIHYDROGEN PHOSPHONOXY)ALKYLOXY CONTAINING A TRIAZOLE DERIVATIVE USED AS ANTIFUNGAL AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-20010041691-A1 | Water soluble prodrugs of azole compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2001-11-15 | — | — | US | disclosed |
| WO-2001052852-A1 | WATER SOLUBLE PRODRUGS OF AZOLE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |
| US-4604409-A | Polyamide-imide foams and methods of making same | IMI-TECH CORPORATION, ELK GROVE, ILL. A CORP. OF | 1986-08-05 | — | — | US | disclosed |
| US-4585805-A | Polyamide-imide foams and methods of making same | IMI-TECH CORPORATION, ELK GROVE, ILL. A CORP. OF | 1986-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041691-A1 | Water soluble prodrugs of azole compounds | CYP51A1, ERG28, CYP7A1 | SMPD1 1988/4885FDPS 702/4885PTPN1 684/4885 |
| US-20020062028-A1 | Process for water soluble azole compounds | CYP51A1, ERG28, CYP7A1 | SMPD1 2265/4885FDPS 423/4885PTPN1 755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.