Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688059 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4ELMNAHTT | |
| SCHEMBL5824224 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4ELMNAHTT | |
| SCHEMBL5824294 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4ELMNAHTT | |
| SCHEMBL10408482 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AKDM4ELMNAHTT | |
| SCHEMBL10408480 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AKDM4ELMNAHTT | |
| SCHEMBL2848279 | 0.81 | KMT2A (0.52) | ALDH1A1KMT2AKDM4ELMNAHTT | |
| SCHEMBL4931645 | 0.81 | KMT2A (0.52) | ALDH1A1KMT2AKDM4ELMNAHTT | |
| SCHEMBL28007809 | 0.80 | LMNA (0.60) | ALDH1A1KMT2AKDM4ELMNAHTT | |
| SCHEMBL31350080 | 0.79 | KMT2A (0.46) | ALDH1A1KMT2AKDM4ELMNAHTT | |
| SCHEMBL75298 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177166-B1 | PROCESS FOR PREPARING (1R,2S,4R) -(-)-2- (2'- N,N-DIMETHYLAMINO -ETHOXY) -2- PHENYL -1,7,7-TRI- METHYL -BICYCLO 2.2.1 HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF | EGIS GYOGYSZERGYAR NYILVANOSAN (HU) | 2008-02-20 | — | — | EP | disclosed |
| EP-1177167-B1 | HIGH PURITY (1R, 2S, 4R)-(-)-2-[(2'-(N,N-DIMETHYLAMINO)-ETHOXY)]-2-[PHENYL]-1,7,7-TRI-[METHYL]-BICYCLO[2.2.1]HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AND MEDICAMENTS CONTAINING THEM. | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2003-10-22 | — | — | EP | disclosed |
| US-6624201-B2 | For use in anxiolytic agents | ORION CORPORATION (FI) | 2003-09-23 | — | — | US | disclosed |
| EP-1052243-B1 | Process for preparing (1R, 2S, 4R)-(-)-2-[(2'-(N,N-dimethylamino)-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2003-07-30 | — | — | EP | disclosed |
| EP-1052245-B1 | High purity (1R, 2S, 4R)-(-)-2-[(2'-(N,N-dimethylamino)-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof, process for the preparation of these compounds and medicaments containing them | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2003-04-16 | — | — | EP | disclosed |
| US-6335469-B1 | COMPOUND CONTAINING NOT MORE THAN 0.2% OF (1R,3S,4R)-3-((2'-(N,N-DIMETHYLAMINO)-ETHYL))-1,7,7-TRIMETHYL -BICYCLO(2.2.1)HEPTANE-2-ONE OR PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | ORION CORPORATION (FI) | 2002-01-01 | — | — | US | disclosed |
| US-6242386-B1 | DRUGS FORMED BY HYDROLYSIS OF CAMPHOR IN THE PRESENCE OF METALLORGANIC COMPOUNDS AND BASIC SALTS | EGIS Gyógyszergyár Rt. (HU) | 2001-06-05 | — | — | US | disclosed |
| EP-1052245-A2 | High purity (1R, 2S, 4R)-(-)-2-[(2'-(N,N-dimethylamino)-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof, process for the preparation of these compounds and medicaments containing them | EGIS GYOGYSZERGYAR RT. (HU) | 2000-11-15 | — | — | EP | disclosed |
| EP-1052243-A2 | Process for preparing (1R, 2S, 4R)-(-)-2-[(2'-(N,N-dimethylamino)-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof | EGIS GYOGYSZERGYAR RT. (HU) | 2000-11-15 | — | — | EP | disclosed |