Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.56 |
| ▸ | CA2 | P00918 | 9/20 | 0.56 |
| ▸ | CA9 | Q16790 | 9/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 9/20 | 0.56 |
| ▸ | DRD1 | P21728 | 6/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671145 | 0.92 | CA1 (0.51) | CA1CA2CA9CA14DRD1 | |
| SCHEMBL28742357 | 0.90 | CA1 (0.69) | CA1CA2CA9CA14DRD1 | |
| SCHEMBL4673775 | 0.83 | DRD1 (0.52) | CA1CA2CA9CA14DRD1 | |
| SCHEMBL28742343 | 0.83 | CA1 (0.68) | CA1CA2CA9CA14DRD1 | |
| SCHEMBL985863 | 0.83 | CA1 (0.55) | CA1CA2CA9CA14DRD1 | |
| SCHEMBL987287 | 0.83 | CA1 (0.52) | CA1CA2CA9CA14DRD1 | |
| Hydrochloric Acid SCHEMBL4674113 | 0.83 | CA1 (0.52) | CA1CA2CA9CA14DRD1 | |
| SCHEMBL985641 | 0.82 | CA1 (0.54) | CA1CA2CA9CA14DRD1 | |
| SCHEMBL8024197 | 0.76 | MAOA (0.60) | CA1CA2CA9CA14DRD1 | |
| Hydrochloric Acid SCHEMBL4674943 | 0.75 | DRD1 (0.47) | CA1CA2CA9CA14DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732898-B1 | TETRAHYDROISOQUINOLINE- AND TETRAHYDROBENZAZEPINE DERIVATIVES AS IGF-1R INHIBITORS | ANALYTECON SA (CH) | 2008-01-23 | — | — | EP | disclosed |