Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 8/20 | 0.48 |
| ▸ | CA2 | P00918 | 8/20 | 0.48 |
| ▸ | CA9 | Q16790 | 8/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4674943 | 0.91 | DRD1 (0.47) | DRD1CA1CA2CA9CA14 | |
| SCHEMBL4412560 | 0.84 | MAOA (0.58) | DRD1DRD2 | |
| SCHEMBL7911741 | 0.84 | MAOA (0.58) | DRD1DRD2 | |
| SCHEMBL4415052 | 0.84 | MAOA (0.58) | DRD1DRD2 | |
| SCHEMBL30799251 | 0.84 | MAOA (0.58) | DRD1DRD2 | |
| SCHEMBL4669747 | 0.83 | CA1 (0.56) | DRD1CA1CA2CA9CA14 | |
| SCHEMBL986382 | 0.83 | CA1 (0.48) | DRD1CA1CA2CA9CA14 | |
| SCHEMBL985708 | 0.83 | DRD1 (0.48) | DRD1CA1CA2CA9CA14 | |
| SCHEMBL985355 | 0.82 | TSHR (0.58) | DRD1CA1CA2CA9CA14 | |
| SCHEMBL28742343 | 0.82 | CA1 (0.68) | DRD1CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732898-B1 | TETRAHYDROISOQUINOLINE- AND TETRAHYDROBENZAZEPINE DERIVATIVES AS IGF-1R INHIBITORS | ANALYTECON SA (CH) | 2008-01-23 | — | — | EP | disclosed |