Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877448 | 0.91 | MAPT (0.45) | CCR2L3MBTL1MAPTMAPK1CXCR6 | |
| SCHEMBL3877452 | 0.91 | MAPT (0.45) | CCR2L3MBTL1MAPTMAPK1CXCR6 | |
| SCHEMBL3880161 | 0.87 | CCR2 (0.56) | CCR2L3MBTL1DRD2MAPTMAPK1 | |
| SCHEMBL3880157 | 0.87 | CCR2 (0.56) | CCR2L3MBTL1DRD2MAPTMAPK1 | |
| SCHEMBL3877519 | 0.82 | MAPT (0.47) | CCR2L3MBTL1MAPTMAPK1CXCR6 | |
| SCHEMBL3877523 | 0.82 | MAPT (0.47) | CCR2L3MBTL1MAPTMAPK1CXCR6 | |
| SCHEMBL3869186 | 0.80 | CCR2 (0.69) | CCR2CXCR6 | |
| SCHEMBL4182888 | 0.80 | CCR2 (0.69) | CCR2CXCR6 | |
| SCHEMBL3869575 | 0.77 | L3MBTL1 (0.53) | CCR2L3MBTL1MAPTMAPK1CXCR6 | |
| SCHEMBL3869568 | 0.77 | L3MBTL1 (0.53) | CCR2L3MBTL1MAPTMAPK1CXCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891064-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | Laboratorios Almirall, S.A. (ES) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006133802-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-12-21 | — | — | WO | disclosed |