Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | CTSG | P08311 | 2/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820695 | 0.77 | SYK (0.38) | CTSKCTSSDPP4MMP12L3MBTL1 | |
| SCHEMBL29013213 | 0.76 | CTSK (0.42) | CTSKCTSSDPP4MMP12MMP13 | |
| SCHEMBL23012930 | 0.75 | MMP13 (0.46) | CTSKCTSSMMP13L3MBTL1PRSS1 | |
| SCHEMBL7729226 | 0.75 | MMP13 (0.46) | CTSKCTSSMMP13L3MBTL1PRSS1 | |
| SCHEMBL7729230 | 0.75 | MMP13 (0.46) | CTSKCTSSMMP13L3MBTL1PRSS1 | |
| SCHEMBL1529633 | 0.74 | KMT2A (0.54) | DPP4MMP12MMP13MMP2MMP9 | |
| SCHEMBL12616798 | 0.74 | MMP13 (0.45) | CTSKCTSSMMP13MMP9L3MBTL1 | |
| SCHEMBL8239858 | 0.74 | CTSK (0.56) | CTSKCTSSMMP9AKT1ADRB2 | |
| SCHEMBL7085232 | 0.74 | DPP4 (0.45) | CTSKCTSSDPP4MMP12MMP13 | |
| SCHEMBL487448 | 0.74 | CTSK (0.49) | CTSKCTSSMMP9PRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792986-B1 | NOVEL CARBONYL REDUCTASE, GENE THEREOF AND METHOD OF USING THE SAME | KANEKA CORP (JP) | 2008-12-31 | — | — | EP | claimed |