Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Quinaldine Blue. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 11/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.98 |
| ▸ | HTT | P42858 | 7/20 | 0.98 |
| ▸ | BLM | P54132 | 3/20 | 0.98 |
| ▸ | THRB | P10828 | 1/20 | 0.98 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.98 |
| ▸ | POLB | P06746 | 6/20 | 0.77 |
| ▸ | RAB9A | P51151 | 6/20 | 0.77 |
| ▸ | MAPT | P10636 | 6/20 | 0.77 |
| ▸ | LMNA | P02545 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.77 |
| ▸ | PKM | P14618 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | ALPG | P10696 | 2/20 | 0.77 |
| ▸ | RECQL | P46063 | 2/20 | 0.77 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.77 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.74 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinaldine Blue SCHEMBL30688825 | 1.00 | MEN1 (0.98) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL636794 | 1.00 | MEN1 (0.98) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL12284820 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL2413213 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL29837418 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL12302233 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL6128354 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL5847479 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL29431896 | 0.98 | MEN1 (0.98) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL58012 | 0.98 | MEN1 (0.98) | MEN1KMT2AHTTBLMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 756 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240345105-A1 | Compositions and Methods for Detecting Analytes in Oral Fluids | GEORGE MASON UNIVERSITY | 2024-10-17 | — | — | US | claimed |
| US-20240091741-A1 | COMPOSITIONS AND METHODS FOR FILTERING MICROORGANISMS FROM A FLUID | GEORGE MASON UNIVERSITY | 2024-03-21 | — | — | US | claimed |
| CN-115838543-A | Photopolymer composition containing organic silicon film forming agent and grating | 杭州光粒科技有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-115840347-A | Photopolymer holographic recording material containing mercapto compound, acrylate compound and epoxy compound and grating | 杭州光粒科技有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-112300098-B | Photopolymer composition, episulfide/epoxy writing monomer and grating | 杭州光粒科技有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-114736749-A | Apparatus for surface decontamination and related compositions and methods | 金诺斯公司 | 2022-07-12 | — | — | CN | claimed |
| US-20220143251-A1 | Device and Related Compositions and Methods for Use in Surface Decontamination | KINNOS INC (US) | 2022-05-12 | — | — | US | claimed |
| CN-109715777-B | Apparatus for surface decontamination and related compositions and methods | 金诺斯公司 | 2022-04-19 | — | — | CN | claimed |
| CN-110845740-B | Cyclodextrin metal framework circular polarization luminescent crystal and preparation method and application thereof | 中国科学院化学研究所 | 2022-02-08 | — | — | CN | claimed |
| US-20210222226-A1 | METHODS OF MEASURING ENZYME ACTIVITY IN COATING COMPOSTIONS | BASF SE (DE) | 2021-07-22 | — | — | US | claimed |
| US-5221590-A | Element having conductive layer in contact with acid photogenerating layer containing a dielectric binder and an onium salt photogenerator | EASTMAN KODAK COMPANY (US) | 1993-06-22 | — | — | US | claimed |
| US-5094545-A | Solid solution with nucleating agent and indicator dye | PYMA CORPORATION (US) | 1992-03-10 | — | — | US | claimed |
| US-5032526-A | Method for the colorimetric determination of sulfonates in aqueous systems | CALGON CORPORATION (US) | 1991-07-16 | — | — | US | claimed |
| US-4894346-A | Method for the colorimetric determination of polycarboxylates in aqueous systems | CALGON CORPORATION (US) | 1990-01-16 | — | — | US | claimed |
| EP-0144130-B1 | METHOD FOR THE COLORIMETRIC DETERMINATION OF POLYGARBOXYLATES AND SULPHONATES INAQUEOUS SYSTEMS | CALGON CORPORATION (US) | 1989-03-01 | — | — | EP | claimed |
| EP-0144130-A1 | Method for the colorimetric determination of polygarboxylates and sulphonates inaqueous systems | CALGON CORPORATION (US) | 1985-06-12 | — | — | EP | claimed |
| US-4345470-A | All plastic disposable thermometer | AKZONA INCORPORATED (US) | 1982-08-24 | — | — | US | claimed |
| US-4339207-A | Temperature indicating compositions of matter | AKZONA INCORPORATED (US) | 1982-07-13 | — | — | US | claimed |
| US-4299727-A | Disposable reversible thermometer | AKZONA INCORPORATED (US) | 1981-11-10 | — | — | US | claimed |
| US-4232552-A | THERMOCHROMISM, DISPOSABLE THERMOMETERS | AKZONA INCORPORATED (US) | 1980-11-11 | — | — | US | claimed |