Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 16/20 | 0.45 |
| ▸ | GABRD | O14764 | 16/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 16/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 16/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 16/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 16/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 16/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 16/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 16/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 16/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 16/20 | 0.45 |
| ▸ | GABRE | P78334 | 16/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 16/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 16/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 16/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 16/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196190 | 0.84 | GABRB3 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7046472 | 0.83 | GABRB3 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3818947 | 0.82 | GABRB3 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9198665 | 0.82 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9192559 | 0.81 | GABRB3 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055701 | 0.80 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055918 | 0.80 | GABRB3 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2835183 | 0.79 | GABRB3 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3824608 | 0.79 | GABRB3 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9192680 | 0.78 | GABRB3 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237873-B1 | CONTROL OF ARTHROPODS IN ANIMALS | MERIAL LTD (US) | 2013-04-03 | — | — | EP | disclosed |
| US-7468381-B2 | Control of arthropods in animals | MERIAL, INC. | 2008-12-23 | — | — | US | disclosed |
| US-20070078127-A1 | Control of arthropods in animals | AVENTIS CROPSCIENCE S.A. (FR) | 2007-04-05 | — | — | US | disclosed |
| US-6992099-B2 | Control of arthropods in animals | AVENTIS CROPSCIENCE S.A. (FR) | 2006-01-31 | — | — | US | disclosed |
| US-20060020013-A1 | Control of arthropods in animals | AVENTIS CROPSCIENCE S.A. (FR) | 2006-01-26 | — | — | US | disclosed |
| US-20030176466-A1 | Control of arthropods in animals | AVENTIS CROPSCIENCE S.A. (FR) | 2003-09-18 | — | — | US | disclosed |
| US-6569886-B2 | Control of arthropods in animals | AVENTIS CROPSCIENCE S.A. (FR) | 2003-05-27 | — | — | US | disclosed |
| EP-1237873-A2 | CONTROL OF ARTHROPODS IN ANIMALS | Bayer CropScience S.A. (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-20020111352-A1 | Control of arthropods in animals | MERIAL, INC. | 2002-08-15 | — | — | US | disclosed |
| WO-2001040195-A2 | CONTROL OF ARTHROPODS IN ANIMALS | AVENTIS CROPSCIENCE S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111352-A1 | Control of arthropods in animals | CTRL, CYP3A43, PON1 | GABRP 2012/4885GABRD 915/4885GABRA1 1127/4885 |
| US-20030176466-A1 | Control of arthropods in animals | CTRL, CYP3A43, PON1 | GABRP 2012/4885GABRD 915/4885GABRA1 1127/4885 |
| US-20070078127-A1 | Control of arthropods in animals | CTRL, CYP3A43, PON1 | GABRP 2012/4885GABRD 915/4885GABRA1 1127/4885 |
| US-20060020013-A1 | Control of arthropods in animals | CTRL, CYP3A43, PON1 | GABRP 2012/4885GABRD 915/4885GABRA1 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.