Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | SCN1A | P35498 | 3/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4675623 | 0.85 | TDP1 (0.39) | TDP1MAPK1CYP2C19TSHRKMT2A | |
| SCHEMBL4669973 | 0.84 | TSHR (0.38) | TDP1LMNATSHRRAB9ACYP2A6 | |
| SCHEMBL4670357 | 0.80 | CYP2C19 (0.37) | TDP1MAPK1CYP2C19SCN1ASCN2A | |
| SCHEMBL12092720 | 0.78 | FFAR4 (0.39) | ALDH1A1 | |
| SCHEMBL12092731 | 0.78 | ACACB (0.39) | ALDH1A1 | |
| SCHEMBL12092733 | 0.78 | FFAR4 (0.39) | ALDH1A1 | |
| SCHEMBL4671965 | 0.77 | CYP2C19 (0.35) | TDP1MAPK1CYP2C19SCN1ASCN2A | |
| SCHEMBL13166557 | 0.77 | MAPK1 (0.41) | MAPK1CYP2C19SCN1ASCN2ASCN3A | |
| SCHEMBL3481487 | 0.76 | MAPK1 (0.40) | MAPK1CYP2C19SCN1ASCN2ASCN3A | |
| SCHEMBL11417714 | 0.76 | MAPK1 (0.40) | MAPK1CYP2C19SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811475-A | REACTING A CARBON WITH A POLYMER HAVING A REACTIVE GROUP AND A HYDROLYZABLE TERT-ALKYL ACRYLIC ESTER; PRINTING INKS; DIELECTRICS; HIGH ELECTRICAL RESISTANCE | NIPPON OIL CO., LTD. (JP) | 1998-09-22 | — | — | US | claimed |
| US-20080124552-A1 | Particle With Rough Surface For Plating Or Vapor Deposition | NISSHINBO INDUSTRIES, INC. (JP) | 2008-05-29 | — | — | US | disclosed |
| US-5821277-A | Thermosetting and procuring compositions for color filters and method for making the same | NIPPON OIL CO., LTD. (JP) | 1998-10-13 | — | — | US | disclosed |