Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1774346 | 0.83 | MAPK1 (0.44) | MAPK1TAAR1ALDH1A1ALOX15KCNN4 | |
| SCHEMBL3481487 | 0.82 | MAPK1 (0.40) | MAPK1TAAR1ALDH1A1ALOX15KCNN4 | |
| SCHEMBL11417714 | 0.82 | MAPK1 (0.40) | MAPK1TAAR1ALDH1A1ALOX15KCNN4 | |
| SCHEMBL16673523 | 0.82 | MAPK1 (0.40) | MAPK1TAAR1ALDH1A1ALOX15KCNN4 | |
| SCHEMBL7535477 | 0.82 | ALDH1A1 (0.42) | MAPK1TAAR1ALDH1A1ALOX15KCNN4 | |
| SCHEMBL19262123 | 0.80 | ESR1 (0.34) | MAPK1ALDH1A1KCNN4MEN1KMT2A | |
| SCHEMBL8314455 | 0.78 | MAPK1 (0.44) | MAPK1TAAR1ALDH1A1ALOX15KCNN4 | |
| SCHEMBL4669945 | 0.77 | MAPK1 (0.36) | MAPK1TAAR1ALDH1A1ALOX15KCNN4 | |
| SCHEMBL984518 | 0.77 | CYP2C19 (0.47) | MAPK1ALDH1A1ALOX15KCNN4KDM4E | |
| SCHEMBL4669947 | 0.77 | TDP1 (0.37) | MAPK1TAAR1ALDH1A1ALOX15KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240856-A1 | Aromatic Ether-Containing Fluorene Monomers, Processes for their Preparation and Polymerization Thereof | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240856-A1 | Aromatic Ether-Containing Fluorene Monomers, Processes for their Preparation and Polymerization Thereof | TYR, PAH, AFF4 | MAPK1 1478/4885TAAR1 2756/4885ALDH1A1 2107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.