Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468 | 1.00 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL521 | 1.00 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL10536032 | 0.97 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL10536037 | 0.97 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL8735384 | 0.93 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8735307 | 0.93 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8735305 | 0.93 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL647 | 0.84 | — | — | |
| SCHEMBL358 | 0.78 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL7326812 | 0.75 | POLB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155118-A | Administering angiotensin inhibitor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| US-5153197-A | Treatment of hypertension with angiotensin II blocking imidazoles | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| US-5138069-A | Treating hypertension and congestive heart failure | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-11 | — | — | US | disclosed |
| US-5128355-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| WO-1989006233-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES AND COMBINATIONS THEREOF WITH DIURETICS AND NSAIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-13 | — | — | WO | disclosed |