Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735384 | 1.00 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8735307 | 1.00 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL468 | 0.93 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL467 | 0.93 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL521 | 0.93 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL10536037 | 0.92 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL10536032 | 0.92 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL215 | 0.77 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL647 | 0.75 | — | — | |
| SCHEMBL7326812 | 0.73 | POLB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733366-B1 | Pharmaceutical compositions comprising angiotensin II receptor blocking imidazoles and diuretics | DU PONT (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0324377-B1 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | DU PONT (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0733366-A2 | Pharmaceutical compositions comprising angiotensin II receptor blocking imidazoles and diuretics | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |