Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL467041

CO[Si](CCCc1nc2ccccc2s1)(OC)OC.S.S.S.S

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.54
HTT P42858 2/20 0.54
ALOX15 P16050 1/20 0.54
MAPT P10636 3/20 0.52
PKM P14618 3/20 0.52
RAB9A P51151 3/20 0.52
NPC1 O15118 2/20 0.52
ALDH1A1 P00352 3/20 0.52
POLB P06746 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
DRD2 P14416 3/20 0.49
HTR1A P08908 1/20 0.49
SLC6A4 P31645 1/20 0.49
HTR7 P34969 1/20 0.49
UBE2T Q9NPD8 1/20 0.49
ASIC3 Q9UHC3 1/20 0.49
HPGD P15428 3/20 0.48
ATM Q13315 1/20 0.48
DRD4 P21917 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911656 0.98 SMN1; SMN2 (0.55) SMN1; SMN2HTTALOX15MAPTPKM
SCHEMBL6139512 0.92 SMN1; SMN2 (0.49) SMN1; SMN2HTTALOX15MAPTPKM
Hydrogen Sulfide SCHEMBL29254226 0.86 SMN1; SMN2 (0.51) SMN1; SMN2HTTALOX15MAPTRAB9A
Hydrogen Sulfide SCHEMBL379530 0.86 SMN1; SMN2 (0.51) SMN1; SMN2HTTALOX15MAPTRAB9A
SCHEMBL6910496 0.85 SMN1; SMN2 (0.54) SMN1; SMN2HTTALOX15MAPTPKM
SCHEMBL6912456 0.84 SMN1; SMN2 (0.52) SMN1; SMN2HTTALOX15MAPTRAB9A
SCHEMBL11125440 0.81 HTT (0.59) SMN1; SMN2HTTALOX15MAPTRAB9A
SCHEMBL9641726 0.81 SMN1; SMN2 (0.70) SMN1; SMN2HTTALOX15MAPTRAB9A
SCHEMBL27509034 0.79 SMN1; SMN2 (0.68) SMN1; SMN2HTTALOX15RAB9ANPC1
SCHEMBL2034241 0.78 SMN1; SMN2 (0.62) SMN1; SMN2HTTALOX15RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1016 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3181626-B1 RUBBER COMPOSITION WITH IMPROVED BIS-SILANE REINFORCEMENT BRIDGESTONE CORP (JP) 2018-10-03 EP claimed
US-9878580-B2 Rubber composition for pneumatic tires for construction vehicles THE YOKOHAMA RUBBER CO., LTD. (JP) 2018-01-30 US claimed
EP-3181626-A1 RUBBER COMPOSITION WITH IMPROVED BIS-SILANE REINFORCEMENT Bridgestone Corporation (JP) 2017-06-21 EP claimed
EP-2658910-B1 RUBBER COMPOSITION WITH IMPROVED BIS-SILANE REINFORCEMENT BRIDGESTONE CORP (JP) 2017-01-25 EP claimed
US-20150336423-A1 Rubber Composition for Pneumatic Tires for Construction Vehicles THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-11-26 US claimed
EP-2658910-A1 RUBBER COMPOSITION WITH IMPROVED BIS-SILANE REINFORCEMENT Bridgestone Corporation (JP) 2013-11-06 EP claimed
US-20130281590-A1 Rubber Composition With Improved Bis-Silane Reinforcement BRIDGESTONE CORPORATION (JP) 2013-10-24 US claimed
US-8534333-B2 Pneumatic tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-09-17 US claimed
WO-2012092062-A1 RUBBER COMPOSITION WITH IMPROVED BIS-SILANE REINFORCEMENT BRIDGESTONE CORPORATION (JP) 2012-07-05 WO claimed
US-7836928-B2 Method of producing a tire composition having improved silica reinforcement BRIDGESTONE CORPORATION (JP) 2010-11-23 US claimed
US-20100288406-A1 PNEUMATIC TIRE THE YOKOHAMA RUBBER CO., LTD. (JP) 2010-11-18 US claimed
US-20060086450-A1 Method of producing a tire composition having improved silica reinforcement BRIDGESTONE CORPORATION 2006-04-27 US claimed
US-20040014869-A1 Method for preparing silica filled elastomeric compositions WONG WAI KEUNG (BE) 2004-01-22 US claimed
EP-0719658-B1 Foamed rubber composition for tires and pneumatic tire using the same BRIDGESTONE CORP (JP) 2000-03-29 EP claimed
US-20240240002-A1 RUBBER COMPOSITION FOR TIRE THE YOKOHAMA RUBBER CO., LTD. (JP) 2024-07-18 US disclosed
CN-118355038-A Modified vinyl aromatic copolymer, method for producing same, modified conjugated diene copolymer obtained from same, resin composition, resin crosslinked product, and structural member 日铁化学材料株式会社 2024-07-16 CN disclosed
US-20240227444-A1 PNEUMATIC TIRE THE YOKOHAMA RUBBER CO., LTD. (JP) 2024-07-11 US disclosed
US-5340867-A Containing synergistic combination of red phosphorus and nitrile group elastomer BRIDGESTONE CORPORATION (JP) 1994-08-23 US disclosed
EP-0541367-A1 Flame-retardant rubber compositions BRIDGESTONE CORPORATION (JP) 1993-05-12 EP disclosed
EP-0447066-A1 Pneumatic tyres Bridgestone Corporation (JP) 1991-09-18 EP disclosed