Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.49 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911656 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTALOX15ALDH1A1MAPT | |
| Hydrogen Sulfide SCHEMBL467041 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTALOX15ALDH1A1MAPT | |
| SCHEMBL11125440 | 0.84 | HTT (0.59) | SMN1; SMN2HTTALOX15ALDH1A1MAPT | |
| SCHEMBL6139512 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTALOX15ALDH1A1MAPT | |
| SCHEMBL9641726 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2HTTALOX15MAPTRAB9A | |
| SCHEMBL27509034 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTALOX15RAB9ANPC1 | |
| SCHEMBL6912456 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTALOX15ALDH1A1MAPT | |
| SCHEMBL2034241 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2HTTALOX15RAB9ANPC1 | |
| Bromide SCHEMBL11522514 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2HTTALOX15RAB9ANPC1 | |
| Hydrogen Sulfide SCHEMBL379530 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2HTTALOX15ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719658-B1 | Foamed rubber composition for tires and pneumatic tire using the same | BRIDGESTONE CORP (JP) | 2000-03-29 | — | — | EP | claimed |
| EP-0708136-B1 | Rubber blend and tread base prepared therefrom | UNIROYAL ENGLEBERT GMBH (DE) | 1999-03-03 | — | — | EP | claimed |
| EP-1069160-B1 | Rubber composition and pneumatic tire formed using the rubber composition | BRIDGESTONE CORP (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6376593-B1 | TIRE TREADS | BRIDGESTONE CORPORATION (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1069160-A1 | Rubber composition and pneumatic tire formed using the rubber composition | Bridgestone Corporation (JP) | 2001-01-17 | — | — | EP | disclosed |