Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830369 | 0.87 | PTGER1 (0.48) | PTGER1PTGER4PTGER3PTGER2CA1 | |
| SCHEMBL11830587 | 0.83 | PTGER3 (0.71) | PTGER1PTGER4PTGER3PTGER2CA1 | |
| SCHEMBL9658945 | 0.83 | PTGER3 (0.71) | PTGER1PTGER4PTGER3PTGER2CA1 | |
| SCHEMBL89145 | 0.80 | CA1 (0.57) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL89143 | 0.80 | CA1 (0.57) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL5613528 | 0.78 | CA1 (0.46) | PTGER1PTGER4PTGER3PTGER2CA1 | |
| SCHEMBL19913000 | 0.78 | CA1 (0.46) | PTGER1PTGER4PTGER3PTGER2CA1 | |
| SCHEMBL18797918 | 0.77 | CA1 (0.52) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL21317661 | 0.77 | PKM (0.56) | CA1CA2CA4NFKB1PKM | |
| SCHEMBL22991749 | 0.76 | CA1 (0.43) | PTGER1PTGER4PTGER3PTGER2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883413-A2 | METHOD OF PREVENTION AND TREATMENT OF AGING, AGE-RELATED DISORDERS AND/OR AGE-RELATED MANIFESTATIONS INCLUDING ATHEROSCLEROSIS, PERIPHERAL VASCULAR DISEASE, CORONARY ARTERY DISEASE, OSTEOPOROSIS, ARTHRITIS, TYPE 2 DIABETES, DEMENTIA, ALZHEIMER'S DISEASE AND CANCER | Omoigui, Osemwota Sota (US) | 2008-02-06 | — | — | EP | disclosed |
| US-20060275294-A1 | METHOD OF PREVENTION AND TREATMENT OF AGING, AGE-RELATED DISORDERS AND/OR AGE-RELATED MANIFESTATIONS INCLUDING ATHEROSCLEROSIS, PERIPHERAL VASCULAR DISEASE, CORONARY ARTERY DISEASE, OSTEOPOROSIS, ARTHRITIS, TYPE 2 DIABETES, DEMENTIA, ALZHEIMERS DISEASE AND CANCER | OMOIGUI OSEMWOTA S | 2006-12-07 | — | — | US | disclosed |
| WO-2006121558-A2 | METHOD OF PREVENTION AND TREATMENT OF AGING, A RELATED DISORDERS AND/OR AGE-RELATED MANIFESTATIONS INCLUDI R C EROSIS. | OMOIGUI OSEMWOTA SOTA (US) | 2006-11-16 | — | — | WO | disclosed |
| US-20060078533-A1 | Method of prevention and treatment of aging and age-related disorders including atherosclerosis, peripheral vascular disease, coronary artery disease, osteoporosis, arthritis, type 2 diabetes, dementia, alzheimer's disease and cancer | OMOIGUI OSEMWOTA S | 2006-04-13 | — | — | US | disclosed |