Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 4/20 | 0.71 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.71 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.71 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | IAPP | P10997 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658945 | 1.00 | PTGER3 (0.71) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL13177051 | 0.86 | PTGER1 (0.56) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL1404989 | 0.85 | IAPP (0.71) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL1404990 | 0.85 | IAPP (0.71) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL7805023 | 0.84 | PTGER2 (1.00) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL7805026 | 0.84 | PTGER2 (1.00) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL690917 | 0.83 | CA1 (0.53) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL691503 | 0.83 | CA1 (0.53) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL4670448 | 0.83 | PTGER1 (0.52) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL30560916 | 0.83 | CA1 (0.53) | PTGER3PTGER2PTGER4PTGER1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998851-A | PREPARATION OF COUMARINS | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-12-21 | — | — | US | disclosed |