Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670487 | 0.86 | DRD2 (0.45) | HDAC1ADRB2ADRB1ADRB3DRD2 | |
| SCHEMBL4670081 | 0.74 | ADRB2 (0.42) | ADRB2ADRB1ADRB3PARP15PARP10 | |
| SCHEMBL4670126 | 0.74 | ADRB2 (0.41) | ADRB2ADRB1ADRB3PARP15PARP10 | |
| Water SCHEMBL4673066 | 0.73 | ADRB2 (0.41) | ADRB2ADRB1ADRB3PARP15PARP10 | |
| SCHEMBL4670057 | 0.73 | PARP15 (0.42) | ADRB2ADRB1ADRB3PARP15PARP10 | |
| SCHEMBL4670413 | 0.73 | PARP15 (0.42) | ADRB2ADRB1ADRB3PARP15PARP10 | |
| Water SCHEMBL4672106 | 0.73 | ADRB2 (0.41) | ADRB2ADRB1ADRB3PARP15PARP10 | |
| SCHEMBL6301319 | 0.71 | PARP10 (0.41) | ADRB2ADRB1ADRB3PARP15PARP10 | |
| SCHEMBL4670624 | 0.71 | PARP15 (0.40) | ADRB2ADRB1ADRB3PARP15PARP10 | |
| Hydrochloric Acid SCHEMBL7392932 | 0.70 | S1PR1 (0.51) | HDAC1ADRB2ADRB1ADRB3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054881-B1 | NOVEL SULFONAMIDE SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER CORP (US) | 2008-07-30 | — | — | EP | disclosed |
| US-6051586-A | HYPOGLYCEMIC AGENTS; ANTIDIABETIC AGENTS | BAYER CORPORATION (US) | 2000-04-18 | — | — | US | disclosed |