Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 1/20 | 0.43 |
| ▸ | TRHDE | Q9UKU6 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669277 | 0.81 | SCN9A (0.49) | DRD2 | |
| SCHEMBL4956555 | 0.77 | ALPI (0.53) | TRHRTRHDEXIAPCYP2C19 | |
| SCHEMBL289025 | 0.77 | ALPI (0.53) | TRHRTRHDEXIAPCYP2C19 | |
| SCHEMBL41832 | 0.77 | ALPI (0.53) | TRHRTRHDEXIAPCYP2C19 | |
| SCHEMBL6527840 | 0.77 | CDK5 (0.47) | TRHRTRHDECYP2C19 | |
| SCHEMBL6069460 | 0.77 | CDK5 (0.47) | TRHRTRHDECYP2C19 | |
| SCHEMBL5717571 | 0.76 | CPB2 (0.47) | TRHRTRHDEXIAPCYP2C19POLB | |
| Hydrochloric Acid SCHEMBL7356305 | 0.76 | CDK5 (0.46) | TRHRTRHDECYP2C19 | |
| Hydrochloric Acid SCHEMBL6527843 | 0.76 | CDK5 (0.46) | TRHRTRHDECYP2C19 | |
| Hydrochloric Acid SCHEMBL6527838 | 0.76 | CDK5 (0.46) | TRHRTRHDECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903052-A2 | APJ receptor ligands and uses thereof | Faust Pharmaceuticals SA (FR) | 2008-03-26 | — | — | EP | disclosed |