Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | CCKAR | P32238 | 4/20 | 0.46 |
| ▸ | CCKBR | P32239 | 4/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054407 | 0.85 | SCN9A (0.64) | SCN9ACCKARCCKBRACECTSS | |
| SCHEMBL3429311 | 0.83 | ACE (0.56) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL17642069 | 0.83 | ACE (0.56) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL6873959 | 0.83 | KLK7 (0.41) | SCN9AKLK7CCKARCCKBRACE | |
| SCHEMBL13792761 | 0.82 | MCHR1 (0.45) | SCN9AKLK7 | |
| SCHEMBL4670787 | 0.81 | TRHR (0.43) | DRD2 | |
| SCHEMBL19508750 | 0.81 | KLK5 (0.51) | KLK7ACECTSSCTSLCTSB | |
| SCHEMBL30064788 | 0.81 | CTSS (0.47) | SCN9AKLK7CCKARCCKBRACE | |
| SCHEMBL5358340 | 0.80 | MAPT (0.46) | KLK7ACECTSSCTSLCTSB | |
| SCHEMBL3957208 | 0.79 | SCN9A (0.58) | SCN9AACECTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170749-A1 | Novel Compounds Which Interact With PEA-15 | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-07-02 | — | — | US | disclosed |
| EP-1903052-A2 | APJ receptor ligands and uses thereof | Faust Pharmaceuticals SA (FR) | 2008-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170749-A1 | Novel Compounds Which Interact With PEA-15 | PEBP1, EPS15, PSTPIP2 | SCN9A 4242/4885KLK7 2623/4885CCKAR 4304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.