Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 6/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.35 |
| ▸ | HTR3A | P46098 | 3/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104574 | 1.00 | HTR1B (0.38) | HTR1BCHRNA7HTR3ADYRK1AHTR3E | |
| SCHEMBL4671711 | 1.00 | HTR1B (0.38) | HTR1BCHRNA7HTR3ADYRK1AHTR3E | |
| SCHEMBL12749946 | 0.86 | HTR1B (0.38) | HTR1BCHRNA7HTR3ADYRK1AHTR3E | |
| SCHEMBL6670562 | 0.83 | HTR1B (0.36) | HTR1BCHRNA7HTR3ADYRK1AHTR3E | |
| SCHEMBL6666042 | 0.77 | HTR1B (0.38) | HTR1BCHRNA7HTR3ADYRK1AHTR3E | |
| SCHEMBL6664622 | 0.72 | DYRK1A (0.36) | DYRK1A | |
| SCHEMBL13073512 | 0.72 | CYP2A6 (0.47) | HTR1BCHRNA7HTR3ADYRK1AHTR3E | |
| SCHEMBL12749944 | 0.71 | HTR1B (0.38) | HTR1BDYRK1AS1PR1S1PR3CDK9 | |
| SCHEMBL11073058 | 0.71 | HTR1B (0.42) | HTR1BCHRNA7HTR3ADYRK1ACDK9 | |
| SCHEMBL6638354 | 0.71 | CYP1A2 (0.50) | HTR3AS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1116795-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE PYRIDINEETHANOL DERIVATIVES | KANEKA CORP (JP) | 2008-03-12 | — | — | EP | claimed |
| US-7329518-B2 | Enzyme for producing optically active pyridineethanol derivatives | KANEKA CORPORATION (JP) | 2008-02-12 | — | — | US | claimed |
| US-20040043460-A1 | Process for producing optically active pyridineethanol derivatives | KANEKA CORPORATION (JP) | 2004-03-04 | — | — | US | claimed |
| EP-1116795-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE PYRIDINEETHANOL DERIVATIVES | KANEKA CORPORATION (JP) | 2001-07-18 | — | — | EP | claimed |
| EP-1116795-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE PYRIDINEETHANOL DERIVATIVES | KANEKA CORP (JP) | 2008-03-12 | — | — | EP | disclosed |
| US-7329518-B2 | Enzyme for producing optically active pyridineethanol derivatives | KANEKA CORPORATION (JP) | 2008-02-12 | — | — | US | disclosed |
| US-20040043460-A1 | Process for producing optically active pyridineethanol derivatives | KANEKA CORPORATION (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1116795-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE PYRIDINEETHANOL DERIVATIVES | KANEKA CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |