Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104140 | 0.77 | DYRK1A (0.37) | KDM4EALDH1A1HSD17B10DYRK1ACDK9 | |
| SCHEMBL12749946 | 0.74 | HTR1B (0.38) | HTR1BDYRK1ACDK9CHRNA7HTR3A | |
| SCHEMBL3122540 | 0.72 | ATM (0.51) | NOS3NOS1NOS2HTR3A | |
| SCHEMBL6670562 | 0.71 | HTR1B (0.36) | HTR1BDYRK1ACDK9CHRNA7HTR3A | |
| SCHEMBL104574 | 0.71 | HTR1B (0.38) | HTR1BDYRK1ACDK9CHRNA7HTR3A | |
| SCHEMBL4671711 | 0.71 | HTR1B (0.38) | HTR1BDYRK1ACDK9CHRNA7HTR3A | |
| SCHEMBL4670935 | 0.71 | HTR1B (0.38) | HTR1BDYRK1ACDK9CHRNA7HTR3A | |
| SCHEMBL102676 | 0.71 | KDM4E (0.39) | KDM4EALDH1A1DYRK1ATAS1R3TAS1R1 | |
| SCHEMBL6930395 | 0.71 | CA2 (0.42) | DYRK1ACHRNA7HTR3A | |
| SCHEMBL843011 | 0.71 | ALDH1A1 (0.42) | ALDH1A1TAS1R3TAS1R1CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| US-4480098-A | Preparation of alkali metal thieno(furo)pyridines | ELI LILLY AND COMPANY (US) | 1984-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | F7, F11, HABP2 | HTR1B 1680/4885KDM4E 1788/4885ALDH1A1 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.