Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671214 | 1.00 | HCAR2 (0.37) | HCAR2OPRM1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5784490 | 0.93 | SMN1; SMN2 (0.40) | HCAR2OPRM1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5784484 | 0.93 | SMN1; SMN2 (0.40) | HCAR2OPRM1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4731230 | 0.86 | NPSR1 (0.44) | HCAR2OPRM1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20109282 | 0.83 | ALDH1A1 (0.39) | OPRM1SMN1; SMN2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL4677408 | 0.78 | ALDH1A1 (0.37) | HCAR2OPRM1SMN1; SMN2ALDH1A1OPRD1 | |
| SCHEMBL4677412 | 0.78 | ALDH1A1 (0.37) | HCAR2OPRM1SMN1; SMN2ALDH1A1OPRD1 | |
| SCHEMBL18134201 | 0.78 | ALDH1A1 (0.46) | OPRM1SMN1; SMN2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL69496 | 0.78 | ALDH1A1 (0.46) | OPRM1SMN1; SMN2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL373936 | 0.77 | ALDH1A1 (0.44) | OPRM1SMN1; SMN2ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304329-B1 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI SANKYO CO LTD (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5849757-A | Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |