SCHEMBL373936

SCHEMBL373936

CCOC(=O)C1(C(C)=O)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.44
HSD17B10 Q99714 1/20 0.44
POLB P06746 1/20 0.39
OPRM1 P35372 6/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALOX15 P16050 2/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
ATM Q13315 1/20 0.37
OPRD1 P41143 3/20 0.37
OPRK1 P41145 3/20 0.37
SLC22A1 O15245 1/20 0.37
SLC6A4 P31645 1/20 0.37
ADRA1A P35348 1/20 0.37
KCNH2 Q12809 1/20 0.37
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5787834 0.91 SMN1; SMN2 (0.42) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL7102497 0.91 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL2321698 0.90 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL18134201 0.88 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL69496 0.88 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL19555323 0.87 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL1833278 0.85 POLB (0.40) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL9070666 0.83 ALDH1A1 (0.35) ALDH1A1LMNAHSD17B10SMN1; SMN2GAA
SCHEMBL374081 0.82 OPRM1 (0.41) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL20109282 0.81 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10POLBOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617762-B2 Carboxy derivatives with antiinflamatory properties SITRYX THERAPEUTICS LIMITED (GB) 2026-05-05 US disclosed
US-12568963-B2 Compounds and compositions for nematode treatment IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2026-03-10 US disclosed
EP-4081511-B3 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2026-03-04 EP disclosed
CN-116730849-B Preparation method of optically active [1- (1-amino ethyl) cyclopropyl ] methanol 江苏艾迪药业股份有限公司 2025-04-29 CN disclosed
WO-2025026266-A1 COMPOUND AS LPAR1 ANTAGONIST, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 武汉朗来科技发展有限公司 2025-02-06 WO disclosed
EP-4442319-A2 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES Sitryx Therapeutics Limited (GB) 2024-10-09 EP disclosed
EP-4081511-B1 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2024-07-31 EP disclosed
US-20240065264-A1 COMPOUNDS AND COMPOSITIONS FOR NEMATODE TREATMENT UNIV IOWA STATE RES FOUND INC (US) 2024-02-29 US disclosed
US-20240059710-A1 KRAS G12D Inhibitors JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2024-02-22 US disclosed
CN-115160116-B Preparation method of cyclopropyl methyl ketone 北京航天试验技术研究所 2024-01-26 CN disclosed
US-5508428-A Spiro compound DAIICHI PHAMACEUTICAL CO., LTD. (JP) 1996-04-16 US disclosed
EP-0578494-B1 24-cyclopropane vitamin D derivatives WISCONSIN ALUMNI RES FOUND (US) 1995-06-14 EP disclosed
EP-0593766-A1 PYRIDONECARBOXYLIC ACID DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1994-04-27 EP disclosed
US-5286723-A Spiro compound DAIICHI SEIYAKU CO., LTD. 1994-02-15 US disclosed
EP-0578494-A1 24-cyclopropane vitamin D derivatives WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1994-01-12 EP disclosed
EP-0357047-B1 Spiro compounds DAIICHI SEIYAKU CO (JP) 1993-11-03 EP disclosed
US-5194431-A 24-cyclopropane vitamin D derivatives WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1993-03-16 US disclosed
EP-0529688-A2 Azaspiro n,m alkanes and diazaspiro n,m -alkanes DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1993-03-03 EP disclosed
EP-0357047-A1 Spiro compounds DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1990-03-07 EP disclosed
EP-0341493-A2 Optically active pyridonecarboxylic acid derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1989-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059710-A1 KRAS G12D Inhibitors KRAS, NRAS, HRAS ALDH1A1 2783/4885LMNA 3252/4885HSD17B10 2326/4885
US-12568963-B2 Compounds and compositions for nematode treatment MASTL, FBXL19, SRMS ALDH1A1 4851/4885LMNA 2420/4885HSD17B10 4558/4885
US-20240065264-A1 COMPOUNDS AND COMPOSITIONS FOR NEMATODE TREATMENT HNMT, TUBB6, SGMS2 ALDH1A1 2714/4885LMNA 2641/4885HSD17B10 2899/4885
US-12617762-B2 Carboxy derivatives with antiinflamatory properties CCR1, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 ALDH1A1 339/4885LMNA 1950/4885HSD17B10 1051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.