Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 20/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 18/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672343 | 0.93 | ADRB2 (0.58) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6283997 | 0.91 | ADRB2 (0.52) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4672072 | 0.89 | ADRB3 (0.42) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6281088 | 0.88 | ADRB2 (0.48) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6281091 | 0.88 | ADRB2 (0.48) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4675124 | 0.85 | ADRB2 (0.46) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6284857 | 0.84 | ADRB2 (0.46) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6284831 | 0.84 | ADRB2 (0.46) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6277983 | 0.84 | ADRB2 (0.46) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4670486 | 0.84 | ADRB3 (0.41) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054881-B1 | NOVEL SULFONAMIDE SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER CORP (US) | 2008-07-30 | — | — | EP | disclosed |