Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 19/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 17/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671845 | 0.85 | ADRB2 (0.57) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4672343 | 0.84 | ADRB2 (0.58) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4670076 | 0.83 | ADRB3 (0.44) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6734914 | 0.83 | ADRB2 (0.47) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4673506 | 0.82 | ADRB3 (0.49) | ADRB2ADRB1ADRB3TSHRHTT | |
| SCHEMBL4672102 | 0.82 | ADRB3 (0.41) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4672101 | 0.82 | ADRB3 (0.41) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4670116 | 0.82 | ADRB3 (0.41) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4670486 | 0.82 | ADRB3 (0.41) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4671887 | 0.82 | ADRB3 (0.41) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054881-B1 | NOVEL SULFONAMIDE SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER CORP (US) | 2008-07-30 | — | — | EP | disclosed |