Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.59 |
| ▸ | CTSK | P43235 | 10/20 | 0.59 |
| ▸ | CTSB | P07858 | 8/20 | 0.59 |
| ▸ | CTSS | P25774 | 8/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2155815 | 0.85 | CTSL (0.54) | CTSLCTSKCTSBCTSS | |
| SCHEMBL2155711 | 0.81 | CTSL (0.78) | CTSLCTSKCTSBCTSS | |
| SCHEMBL28457933 | 0.81 | CTSL (0.83) | CTSLCTSKCTSBCTSS | |
| SCHEMBL28457934 | 0.81 | CTSL (0.83) | CTSLCTSKCTSBCTSS | |
| SCHEMBL2156792 | 0.81 | CTSL (0.83) | CTSLCTSKCTSBCTSS | |
| SCHEMBL28457932 | 0.81 | CTSL (0.83) | CTSLCTSKCTSBCTSS | |
| SCHEMBL2156361 | 0.81 | CTSK (0.67) | CTSLCTSKCTSBCTSS | |
| SCHEMBL4675215 | 0.80 | CTSK (0.48) | CTSLCTSKCTSBCTSS | |
| SCHEMBL2157033 | 0.77 | CTSL (1.00) | CTSLCTSKCTSBCTSS | |
| SCHEMBL8354274 | 0.77 | CTSL (0.76) | CTSLCTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482924-B1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-05-21 | — | — | EP | disclosed |