Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | QDPR | P09417 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027001 | 0.90 | IDO1 (0.55) | IDO1CCNCCDK8RECQLLOX | |
| SCHEMBL3500189 | 0.84 | MAP4K4 (0.49) | MAPTIDO1CCNCCDK8RECQL | |
| SCHEMBL29461217 | 0.84 | ADORA2A (0.56) | IDO1CCNCCDK8NOTUMRECQL | |
| SCHEMBL2329610 | 0.84 | ADORA2A (0.56) | IDO1CCNCCDK8NOTUMRECQL | |
| SCHEMBL25070215 | 0.82 | ADORA2A (0.54) | IDO1CCNCCDK8NOTUMCYP19A1 | |
| SCHEMBL4753951 | 0.80 | IDO1 (0.49) | IDO1SMARCA2SMARCA4CCNCCDK8 | |
| SCHEMBL27722982 | 0.80 | IDO1 (0.44) | IDO1CCNCCDK8RECQLLOX | |
| SCHEMBL28163101 | 0.80 | CCNC (0.46) | MAPTIDO1CCNCCDK8AAK1 | |
| SCHEMBL12050763 | 0.80 | ESR2 (0.47) | MAPTIDO1CCNCCDK8RECQL | |
| SCHEMBL4932513 | 0.80 | MAPK14 (0.52) | MAPTIDO1CCNCCDK8RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116726994-B | Preparation method and application of Salen (M) porous ionic polymer heterogeneous catalyst | 昆明理工大学 | 2024-11-22 | — | — | CN | claimed |
| CN-116726994-A | Preparation method and application of Salen (M) porous ionic polymer heterogeneous catalyst | 昆明理工大学 | 2023-09-12 | — | — | CN | claimed |
| CN-116239517-A | All-organic perovskite material and preparation method thereof | 南方科技大学 | 2023-06-09 | — | — | CN | claimed |
| CN-111925321-B | Paraquat hapten, complete antigen, antibody, detection test paper and kit | 北京纳百生物科技有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-111925321-A | Paraquat hapten, complete antigen, antibody, detection test paper and kit | 北京纳百生物科技有限公司 | 2020-11-13 | — | — | CN | claimed |
| CN-116726994-B | Preparation method and application of Salen (M) porous ionic polymer heterogeneous catalyst | 昆明理工大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-114904356-B | Method for separating nitrogen and oxygen | 中国科学院大连化学物理研究所 | 2024-03-26 | — | — | CN | disclosed |
| CN-116726994-A | Preparation method and application of Salen (M) porous ionic polymer heterogeneous catalyst | 昆明理工大学 | 2023-09-12 | — | — | CN | disclosed |
| US-20230271960-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS INC (US) | 2023-08-31 | — | — | US | disclosed |
| US-20230181546-A1 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | PLIANT THERAPEUTICS INC (US) | 2023-06-15 | — | — | US | disclosed |
| CN-116239517-A | All-organic perovskite material and preparation method thereof | 南方科技大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-114904356-A | Method for separating nitrogen and oxygen | 中国科学院大连化学物理研究所 | 2022-08-16 | — | — | CN | disclosed |
| EP-1503757-A4 | TYROSINE KINASE INHIBITORS | MERCK & CO INC (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20050176753-A1 | controlling signal transduction; anticancer agents; antitumor agnets; atherosclerosis; vision defects; antidiabetic agents; antiinflammatory agents | MERCK SHARP & DOHME CORP. | 2005-08-11 | — | — | US | disclosed |
| EP-1503757-A2 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003092595-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC (US) | 2003-11-13 | — | — | WO | disclosed |
| US-6174901-B1 | FOR TREATMENT OF RHEUMATOID ARTHRITIS, PAGETS DISEASE, OSTEOPHOROSIS, MULTIPLE MYELOMA, UVEITITIS, ACUTE OR CHRONIC MYELOGENOUS LEUKEMIA, PANCREATIC .BETA. CELL DESTRUCTION, OSTEOARTHRITIS, RHEUMATOID SPONDYLITIS, GOUTY ARTHRITIS ETC. | AMGEN INC. | 2001-01-16 | — | — | US | disclosed |
| EP-1042293-A1 | SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | Amgen Inc. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032448-A1 | SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | AMGEN INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| US-4550166-A | SEDATIVES, TRANQUILIZERS, TENSION REDUCERS | AMERICAN CYANAMID COMPANY (US) | 1985-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271960-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | ITGB6, ITGA6, ITGA5 | LMNA 3365/4885MAPT 3892/4885IDO1 2131/4885 |
| US-20050176753-A1 | controlling signal transduction; anticancer agents; antitumor agnets; atherosclerosis; vision defects; antidiabetic agents; antiinflammatory agents | IRAK4, MAP3K4, MAP3K1 | LMNA 4430/4885MAPT 1620/4885IDO1 767/4885 |
| US-20230181546-A1 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | ITGA5, ITGAL, ITGB5 | LMNA 3362/4885MAPT 4071/4885IDO1 4293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.